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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b41be53f6825f83dcd6e492690c45f5decb9ddb2eec3cd5799c39e0fea75de0b' 
  AND token = 'Afoc6c/ccfigijIRNmyP+sxFEOEekGWNuCc3IApWgcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}