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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a2cf18b5a9e70a34ef25e528aff991102e700c661ae1302f1782ef915bde72f' 
  AND token = 'BReaonCvFu6TDWHKuGlSK9r6YrSm9K0yiSXsFhqO3wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}