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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48b5c61f9f410a8d10179eb0e8ff010eb6cd06ed6ff76fc1f1c9993fcfcc5f3e' 
  AND token = '7fsgGAxg7IX5YSJno6EdEhRdSPLJGrnU+cU6HncA/74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}