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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72091bd0cc88979f8629b5d19b099437a1e876a2c92b8fcc73bfd4e986ead05' 
  AND token = 'Pl1pKlOf3aEbgBJ9/O71zW4ZJ2hnMLrrYqFIen6L+SE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}