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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a0c66f9df8a3b9b0264a86a83f59746f1870b09912ba0955a12d5a77bcc3ba' 
  AND token = 'QXarIYXVAKuzvJ0S945dPUKfQiPLh+E0v2gFcO5b21E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}