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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18eaf3aa7793c8193ac0c9e410c0878cc904f5b91a08d33077a0e9f38e6bea0b' 
  AND token = 'bSLbjdTSKVH5k9Ka3NdgNohbg9bfdt+Uufgi/33IVUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}