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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '613275c4c89bc5138b8883384c946cf7a8a5fcff5a0d3c5ed28f5189738c2511' 
  AND token = 'vVWUS/U2MNQwENQD9r1ycHZsXWAaPf9wiY76JN1CiiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}