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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e88a6ac49ab83bfea1e69bbae7681bf3a9a89f061dabf30d17be73716b178812' 
  AND token = 'Q29qwh1RtfMQHavwVKa2vsqxXvetLAx791npCMAPOoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}