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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd228d61da3ccfd5bbfa637719c21171d4c52d731cfc24c4b500cd7c057df43ee' 
  AND token = '27UMVF9HKIWMG4WlOxIrePS5lgHnDRoQ4VcGGZTxUIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}