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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6071d0ea1f088db51ceeedab229c91a711796df66aa7d96d749f7d517d45e23' 
  AND token = 'ICDJEae99AD1ZMz3u1pDd9GLW2XCzNMmnQAT7taEkSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}