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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643e95ac7405c6b33a8a65fcc39b55e4ef9662e7000fd8b3d8ffa79d39addd20' 
  AND token = 'Z/M8mukrHIprKb1pVJSF5nZSFOLxdwMxQPkEuIy40Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}