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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9181469f040431dfd1ffcfe1286761c2c9da608636b88b6b132ccd425f2ba81' 
  AND token = '059O9mgBZItvft8VHHcAfWSR2r2ST3ocjp/Q1gnTQUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}