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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a0a9c9e328bda8723499cc4e9e4900f5a18416fa5f8223da6060219843e4f89' 
  AND token = '77gDOOaxJKAOmwJMN4RPPy/XJUiZStGIVRIjmU8bhUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}