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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e015425680df0cee38f51a2f4d4f99c2aa316abb00f9af4d591213b9a2040e9' 
  AND token = 'U9waNTz4UHWErK5a81i0HwwJsGtbwKLXiRRBZFIaE9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}