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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4f2bf28f3e94333445cf9eda07d1cc53f81b6443a06cfa4a2e4103e21e212af' 
  AND token = 'jXsDych0mHgcMXnpWaoNGufE6AoQBD8Lm7E7W77WTBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}