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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '417609fd3f5b8492f9b1f5ac475acca8c1e02b8bb9749a15752908e72f866afa' 
  AND token = 'fmnjYIKE6OZeNGHhuQG+rajZ1FYRJSnGy78bwK6j2i8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}