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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a17f95502278e0e74b3287b14dc7159b49c65711cc94167f7dbbdf02dff14c7' 
  AND token = 'QUpahwVZj+flyl0NZEAm8IRGpPbHUAZP+99mgIa060I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}