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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b5c998073ea1eb8493359242a74e317f41022201cc5b6b9a8cee4ddfe63cf9b' 
  AND token = 'O3tf1YUhROwtjaJcfuBRaLMu5TtWxQO3nGSPLejzRII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}