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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a5343abdf925a73a4ba89113b28e01b105985d0c665db45734303fbdecbd0a4' 
  AND token = '4bIJfrNznzJI+SxcTe9l5j3/zFDtN5U0rXE3fwswmt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}