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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '608dd0e2467bdbf046426f6d78a6f237ad6ded5a5e6150e4dac63684291d0e46' 
  AND token = 'SCE6KOFbjgiqzXVKdWIgKTWo7CLWSaN1zG1wGHX+mdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}