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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3abd4583733ee292f998101613f2b1f5e3a0a11b0609ca30c9d49281b9e23593' 
  AND token = '4VDCKb0aWWPVNeDRA16sDDGx/zCvwLvxGpWND4nFKZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}