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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9b078cbcff726a5487cefb06976d5350a17baa785418373cbee51d22620365f' 
  AND token = 'P2VoS/A3CiM//+215pollwmj5OoZ1CaTJoISgNSKgTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}