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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c05f3cd9c289462005cd4d6c7b59fea8e5a4004db64ef2d1f6997d7bab66f8a' 
  AND token = '1cqTk2YzoLY6l+RNK4lz+EjJmYwWYrwzWha5R8DQ3cE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}