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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ebf8663c58eff367cc8b280e0e83bdc05be79cc37e798cc0557168646558dc1' 
  AND token = 'RpPnII8no4YXjoEgP7FKtp4WdK4w9NWj2ApMllDZYpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}