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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57318a370850c6f317239745e9c041bfe9609725354ffd84b8c2fbd50d123742' 
  AND token = 'Y4TIUrOQmf77AZIZp02odZE+8ZRc4ODlTIiAmM3K1Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}