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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '198377d36a859bd0102949e2df8b68f6740c8e427c51fd8968d88e8709285e98' 
  AND token = '+KGlYpzRf9W9HPAAgtSVESc+XcbaWd1qO/5Mu8mctIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}