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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0b61d3e319fe46f05023e3bd25daf114223e1cad62b5171e91491ebbadb4ff8' 
  AND token = 'hn7YCci7bB3MjG6hnGub9pDUmB7Ox288H47IC87Xux4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}