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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd28b3ce4f63c0d8596c5770ddecb2f509763844ce6a4e0c472e5cd55d5cf5d32' 
  AND token = 'Qyal3d/FnaTRNTo1OESXB0GPN6UvCT0h7UifEtsRgQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}