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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00e61cf13e7c436b2c2121ef32cd465f2b30b48f268b1e677e62653e14ccace2' 
  AND token = 'aTpDXJFHxQXDWNRHux3i9+JMV47NRQhMTQQP+4vv9yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}