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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad1000feca9d543a0e49ff2d47fbe81477527bbbd7b2272a96034f0260e551f4' 
  AND token = 'Wvzd54tZhJL9UgOdi26J1iKaf3UFc0T0c/T1IADxR8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}