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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9c3d478bf9201f80fe4faebb2e73f1474f6cd0a2511a2b68204d712a2665d2f' 
  AND token = 'Qf4JNAzCfdSSMP0knT+0NbIOFoXrXMY7L7FsuL9MNK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}