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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2405366845743858be61aa5ddd2fcc5fcc7af108e340a0542aa5d07f59c64198' 
  AND token = 'b25/mbPkyZ5PwL8c3r2vKh4BXV92ddGzjJ5xsW1Q3Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}