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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6281f10cafa40a214ad706f8745919e9b85a7a45d4b202493a49003eb7dd756' 
  AND token = 'uLThQ6S2VOinkbndx4GdbeMmR+d4O620R22bMxsEeVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}