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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d5c5cf201ec0035b82c950ac4f6f4f2a314fb51df2ffef902a7e824725fa4d' 
  AND token = 'th/SvXnlDTuTe6cJAwC9RmesQkJtZVqGe/K/1Ng3lGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}