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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '330595089032d5c1e9f610b00270bdb9a450aaa17e57b12828842bbee26eb68f' 
  AND token = 'H/VNFL0zW0l/Brt6p+EiXA4QxdoknGazX+Ktf1KD7ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}