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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e85dbbe1fac586c46d807168a02fc44a1ed6ec54482bda024fdc889afeda22b' 
  AND token = '5Dgohb43XigcDF9V3ItR+ehQLxh5LCK1Jaw0wVqZH8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}