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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '367765a6ac13dbcff421531871d19757755d5f20b587e8ac752326f4df223daa' 
  AND token = '8+MN/2o1sGG0v4GHB5tq0Hd6H+jdLk9xtRhPRm8hjz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}