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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20ada854fb401f79d4b84180e14331280b75c0dff107505eb099d0c665fde0a4' 
  AND token = 'YiWi7R9xvTEkpqxtuCQBFuBZ1J/+Hr5cAjcRKxnDy8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}