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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2683449cb713e4db8c18605d52f2f4190ae3b86175347decdf9e715c50bbb4' 
  AND token = '8KB8V80kNWV8zRFqUv5tH6nYBAnHGJ4al218Tk8ga/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}