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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f33369c2a5f3b1505ca913aa5e0850b6cb73a9210c9ca3d94f77556fa329f7c8' 
  AND token = 'ysBKG3F9xJ9xo3lVJemEFQqGjeq7e0KyrSrHr55/FiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}