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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '147dd49bd7357b65e0f282589235fee00d404a9b679086c85c3fc0ba80adb591' 
  AND token = 'F3eM4vSBD4o/I6UoSQjkurNFV3nlNjCivB5qytLseGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}