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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a1bfc30f8068d25741be6fa5d7334edc51843a64f41b382f65109186faa7c09' 
  AND token = 'Xhul3YlaIoMDI7hbUFU0W/fZ1uQf9Hn/FKLrub5K1qU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}