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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5d409ee5bba994b1de3e414c4d016e6ca55619c1c2d4de8e3bb1808053e377f' 
  AND token = 'L6cU2zSgg2GrSxIOpGVNYpuXUb1BupYuUiHZv6OY3T4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}