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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3de99ec168033d33ff13ccba6d420426e917b115e69a415942d6a5b51da76b6c' 
  AND token = '+CuLb8rxEgk0PCV/KxoWoikG6tbmXU0u3ZF4tyUadTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}