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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccdf43e415f61a8228bdb6b1cbee7926ec0c7f15b26963bca9e4d3181bbd486d' 
  AND token = 'EdGKekaVnM1GfOC0Ix92+SZHYUD03EIVxTgowaEKc7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}