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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c73e6e522fb0b91a1354167d24c70e2c80d413da2703e7c47cca491d134932b' 
  AND token = 'pNArk4NkFTi1SHd9XU+2omb0Jcddd8eGYavwCAibDvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}