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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ee248ebfc8c272195c6286f708a5e7ef334001865c403dd02323cd4c12b1114' 
  AND token = 'CcrdCWc4dC5YILxJUoX/oEsTTeFIxRG9RaazYU4BMIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}