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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe94b5bf5381d4d6e32059b30781e3b460f47786724fa58cbbf4d3498c17ee9c' 
  AND token = 'EyXyVtvwoLRkPPQ4xStfQpd0HtGpRuqlWY66lEdTAdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}