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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '599fa0927e0277c5ed2941a95c95235bb405f669ba6d35a19b3ec5b544d2da2f' 
  AND token = 'ZmS/UHkYkiToK/Q9fvdwncZ5LpkdJ28K192EgZ7nR5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}