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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ff75f2e00f3c721433add56c5b006b5b1c9070a534b9ef4eb94c3babe8c1bed' 
  AND token = '/T6cDIcM27+OgwNNkapYXTcWiqjASY4fvJM70+YICas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}